Jian Huang

Jian Huang

PhD candiate, Computational Biophysics

List of Publications


    2024

  1. V. Burtscher, J. Mount, J. Huang, J. Cowgill, Y. Chang, K. Bickel, J. Chen, P. Yuan, and B. Chanda. Structural Basis for Hyperpolarization-dependent Opening of Human HCN1 Channel. Nature Communications. under revision.
  2. V. Nguyen*, C. Özden*, K. Dong, A. Ocampo, N. Dziedzic, D. Flaherty, J. Huang, D. Tomchick, J. Chen, S. Garman, M. Stratton. CaMKII variable linker-mediated allosteric regulation of Ca2+/CaM sensitivity through a domain-swapped conformation. (submitted)

    3. 2023

  3. Huang, J., Korsunsky, A., Yazdani, M., & Chen, J. Targeting TRP Channels: Recent Advances in Structure, Ligand Binding and Molecular Mechanisms. Frontiers in Molecular Neuroscience. (2023). Available Online
  4. Huang, J. & Chen, J. Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4. Commun Biol 6, 1–9 (2023). PUBMED. DOI

    5. 2022

  5. Jia, Z.#, Huang, J.# & Chen, J. Activation of TMEM16F by inner gate charged mutations and possible lipid/ion permeation mechanisms. Biophysical Journal 121, 3445–3457 (2022). PUBMED. DOI.

    6. 2021

  6. Xue T., Wu W., Guo N., Wu C., Huang J., Lai L., Liu H., Li Y., Wang T., Wang Y. Single point mutations can potentially enhance infectivity of SARS-CoV-2 revealed by in silico affinity maturation and SPR assay. RSC Adv. 2021 May 10. PUBMED. DOI.
  7. Fu Y.#, Huang J.#, Wu Y., Liu X., Zhong F., Wang J. Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase. J Am Chem Soc. 2021 Jan 20;143(2):617-622. PUBMED. DOI.